L00402 ToxinEraser™ Endotoxin Removal Resin
| 參考價 | ￥ 500 |
| 訂貨量 | ≥1件 |
- 公司名稱 漠寶（廈門）生物科技有限公司
- 品牌 GenScript/金斯瑞
- 型號 L00402
- 產地
- 廠商性質 代理商
- 更新時間 2025/7/22 9:57:32
- 訪問次數 82
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| 供貨周期 | 一周 | 規格 | 1 ml Resin (Total 2 ml) |
|---|---|---|---|
| 貨號 | Removal Resin | 應用領域 | 醫療衛生,環保,食品/農產品,生物產業,制藥/生物制藥 |
| 主要用途 | 利用固定化的多粘菌素B來結合并清除溶液中的致熱原 |
The ToxinEraser™ Endotoxin Removal Resin utilizes immobilized polymixin B to bind and remove pyrogens from solution. The polymixins are a family of antibiotics that contain a cationic cyclopeptide with a fatty acid chain. Polymixin B neutralizes the biological activity of endotoxins by binding to the lipid A portion of bacterial lipopolysaccharide.
Description
Lipopolysaccharide (LPS) is a bacterial endotoxin, and a major constituent of the cell walls of gram-negative bacteria. During gram-negative bacteremia or endotoxemia, LPS is the principal pathophysiological mediator by which bacteria can cause hypotension, organ failure, disseminated intravascular coagulation, and fatal shock in mammalian hosts. The removal of these endotoxins is highly necessary for downstream processes.
The ToxinEraser™ Endotoxin Removal Resin utilizes immobilized polymixin B to bind and remove pyrogens from solution. The polymixins are a family of antibiotics that contain a cationic cyclopeptide with a fatty acid chain. Polymixin B neutralizes the biological activity of endotoxins by binding to the lipid A portion of bacterial lipopolysaccharide.
產品概述
Product Information
Binding Capacity： Up to 2,000,000 EU/ml resin.
Ligand： Modified PMB (Polymixin B)
pH Stability： pH 5 -10
Support Matrix ：4% cross-linked agarose, spherical beads
Mean Particle Size ：90 μm
Types of substances that can be applied to the column ：Protein, including peptides and antibody, polysaccharide, etc.
Applicable Ionic Strength ：0.1 to 0.5 M NaCl
Substances tested that do not interfere with performance： 20% DMSO, 20% ethanol, 20% glycerol; 1 M urea, 300 mM imidazole; 0.05% Tween 20, 10 mM DTT, etc.
Key Features
High stability and high removal efficiency.
High binding capacity: > 2, 000, 000 EU / ml (CV).
Reusable up to five times if properly regenerated.
產品屬性
Storage & Stability ：2°C to 8°C (Do not freeze.)
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