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【產品簡介】
【詳細說明】
Huwentoxin-XVI
Huwentoxin-XVI is a selective blocker of N-type Ca2+channels
N型Ca2+通道選擇性阻斷劑
is a 39 amino acids peptide that was discovered from the venom of the Chinese tarantula Ornithoctonus huwena. was shown to be a potent blocker of HVA N-type calcium channels with an IC50 value of 60 nM in rat DRG. The blocking effect appears to be similar to that of ω-conotoxin-GVIA and ω-conotoxin-MVIIA. Neverthelss, differs from GVIA and MVIIA thanks to its greater reversibility and its higher selectivity for N-type over P/Q type than MVIIA.
Huwentoxin-XVI技術資料
氨基酸序列：
Cys1-Ile-Gly-Glu-Gly-Val-Pro-Cys8-Asp-Glu-Asn-Asp-Pro-Arg-Cys15-Cys16-Ser-Gly-Leu-Val-Cys21-Leu-Lys-Pro-Thr-Leu-His-Gly-Ile-Trp-Tyr-Lys-Ser-Tyr-Tyr-Cys36-Tyr-Lys-Lys-OH
二硫鍵：Cys1-Cys16, Cys8-Cys21 and Cys15-Cys36
長度 (aa)：39
分子式：C196H292N50O56S6
分子量（平均）：4437.2 Da
外觀：White lyophilized solid
CAS 號：Not available
來源：Synthetic
純度：> 98%
產品信息
貨號 | 名稱 | 規格 |
N/A | 100ug/500ug/1000ug |
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