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ANO3 rabbit pAb
  • ANO3 rabbit pAb
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更新時(shí)間:2025-03-10 21:00:08

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SourceRabbitApplicationsWBReactivityHuman
  • Source

    Rabbit

  • Applications

    WB

  • Reactivity

    Human, Mouse

  • Dilution

    WB 1:500-2000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of ANO3 at Human/Mouse

  • Source/Purification

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthesized peptide derived from human ANO3

  • Uniprot No

    Q9BYT9

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, that are also known as anoctamins. While little is known about the function of this gene, mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with, and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015],

  • Other

    ANO3 C11orf25 TMEM16C GENX-3947, ANO3

  • Mol.Wt (Da)

    107910

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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