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Rabbit
IHC,ELISA
Human,Mouse,Rat
IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
-20°C/1 year
AZ1 Polyclonal Antibody detects endogenous levels of AZ1 protein.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
The antiserum was produced against synthesized peptide derived from human OAZ1. AA range:14-63
P54368
OAZ1; OAZ; Ornithine decarboxylase antizyme 1; ODC-Az
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Polyclonal
IgG
ornithine decarboxylase antizyme 1(OAZ1) Homo sapiens The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs; and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms
OAZ1, Ornithine decarboxylase antizyme 1
25406
1 mg/ml
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