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Bombesin Receptor 2 rabbit pAb
  • Bombesin Receptor 2 rabbit pAb
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更新時間:2025-06-28 11:56:29

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SourceRabbitApplicationsWB,IHCReactivityRat,MouseDilutionWB:1:500-1:2000
  • Source

    Rabbit

  • Applications

    WB,IHC

  • Reactivity

    Rat,Mouse

  • Dilution

    WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    The antibody detects endogenous Bombesin Receptor 2 protein

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthetic Peptide of Bombesin Receptor 2

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.

  • Other

    ,

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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