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Brk (phospho Tyr447) rabbit pAb
  • Brk (phospho Tyr447) rabbit pAb
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更新時間:2025-06-28 13:09:09

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SourceRabbitApplicationsWB,IF,ELISAReactivityHumanDilutionWB:1:500-1:2000
  • Source

    Rabbit

  • Applications

    WB,IF,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Phospho-Brk (Y447) Polyclonal Antibody detects endogenous levels of Brk protein only when phosphorylated at Y447.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human Breast Tumor Kinase around the phosphorylation site of Tyr447. AA range:402-451

  • Uniprot No

    Q13882

  • Alternative names

    PTK6; BRK; Protein-tyrosine kinase 6; Breast tumor kinase; Tyrosine-protein kinase BRK

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    protein tyrosine kinase 6(PTK6) Homo sapiens The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012],

  • Other

    PTK6, Protein-tyrosine kinase 6

  • Mol.Wt (Da)

    51834

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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