DOTA-GRGDSP，DOTA偶聯多肽GRGDSP

名稱：DOTA-GRGDSP，DOTA偶聯多肽GRGDSP

GRGDSP 是一種合成的線性RGD肽，是一種整聯蛋白 (integrin) 抑制劑。

GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.

It is demonstrated that transarterial infusion of GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro integrin-inhibitor which includes RGD-peptide). As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis[1]. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. GRGDSP can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization.

中文名稱：GRGDSP

英文名：GRGDSP

CAS號：91037-75-1

單字母：H2N-GRGDSP-OH

三字母：H2N-Gly-Arg-Gly-Asp-Ser-Pro-COOH

氨基酸個數：6

分子式：C22H37N9O10

平均分子量：587.58

***分子量：587.27

等電點(PI)：6.34

pH=7.0時的凈電荷數：-0.02

平均親水性：2.1

疏水性值：-1.87

來源：Synthetic

純度：95%、98%

鹽體系：可選TFA、HAc、HCl或其它

生成周期：2-3周

相關試劑列表：

DOTA-Stearyl-R8 DOTA偶聯細胞穿膜肽Stearyl-R8

DOTA-HIV-Tat DOTA偶聯細胞穿膜肽HIV-Tat

DOTA-PTD-5 DOTA偶聯細胞穿膜肽PTD-5

DOTA-TAT(48-60)-NH2 DOTA偶聯細胞穿膜肽TAT(48-60)-NH2

DOTA-Tat(48-61) DOTA偶聯細胞穿膜肽Tat(48-61)

DOTA-plsl DOTA偶聯細胞穿膜肽plsl

DOTA-VP22 DOTA偶聯細胞穿膜肽VP22

DOTA-SynB1 DOTA偶聯細胞穿膜肽SynB1

DOTA-L17E DOTA偶聯細胞穿膜肽L17E胞質輸送肽

DOTA-P-alpha DOTA偶聯細胞穿膜肽P-alpha

DOTA-Transportan DOTA偶聯細胞穿膜肽Transportan

DOTA-POD DOTA偶聯眼部轉運肽POD

DOTA-RVG DOTA偶聯狂犬病病毒肽RVG

DOTA-B6 peptide DOTA偶聯細胞滲透肽B6