久久国产精品午夜一区_91精品國產高清久久久久久91_?级毛片免费全部播放_欧美色图在线视频一区二区三区_国产综合亚洲一区二区三区_中文字幕熟女网_国产精品男人爽免费视频_九九无码网战_亚洲日本三级电影在线观看_欧美日韩DVD手机在线不卡

BPS Bioscience Inc.
中級會員 | 第3年

當前位置:BPS Bioscience Inc.>>試劑>>藥物篩選>> SRT1720

SRT1720

參  考  價面議
具體成交價以合同協議為準

產品型號

品       牌BPS Bioscience

廠商性質生產商

所  在  地

更新時間:2023-12-19 23:35:35瀏覽次數:194次

聯系我時,請告知來自 化工儀器網
同類優質產品更多>
保存條件:Roomtemp
  • 保存條件:

    Room temp. (continental US) or gel packs

  • 保質期:

    Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

  • 英文名:

    SRT1720

  • 數量:

    1

  • 供應商:

    BPS Bioscience Inc.

  • CAS號:

    /

  • 規格:

    5 mg

SRT1720 is a small-molecule compound which has the ability of activating the sirtuin subtype SIRT1 in vitro. SRT1720 has similar activity in the body to the known SIRT1 activator resveratrol, but is 1000x more potent. It affects mitochondrial respiration in a Sirt1- and PGC-1α-dependent manner. SRT1720 has been demonstrated to enhance insulin sensitivity and improve measures of mitochondrial capacity and oxidative metabolism. Treatment of multiple myeloma (MM) cells with SRT1720 inhibits growth and induced apoptosis in MM cells resistant to conventional and bortezomib therapies without significantly affecting the viability of normal cells. SRT1720 is able to enhance the cytotoxic activity of bortezomib or dexamethasone. Anti-MM activity of SRT1720 is related to: 1) activation of caspase-8, caspase-9, caspase-3, poly(ADP) ribose polymerase; 2) increase in reactive oxygen species; 3) induction of phosphorylated ataxia telangiectasia mutated/checkpoint kinase 2 signaling; 4) decrease in vascular endothelial growth factor-induced migration of MM cells and associated angiogenesis; and 5) inhibition of nuclear factor-κB.
溫馨提示:不可用于臨床治療。

會員登錄

×

請輸入賬號

請輸入密碼

=

請輸驗證碼

收藏該商鋪

X
該信息已收藏!
標簽:
保存成功

(空格分隔,最多3個,單個標簽最多10個字符)

常用:

提示

X
您的留言已提交成功!我們將在第一時間回復您~
撥打電話
在線留言
主站蜘蛛池模板: 兴山县| 嘉兴市| 西青区| 蕉岭县| 沁水县| 都兰县| 汝城县| 扶风县| 新绛县| 饶河县| 新河县| 安图县| 宕昌县| 定日县| 青田县| 岫岩| 砀山县| 阿图什市| 仁化县| 库尔勒市| 哈巴河县| 侯马市| 平泉县| 海兴县| 宜君县| 云南省| 繁昌县| 嵩明县| 河北省| 肇州县| 湖州市| 松潘县| 肇源县| 白城市| 剑河县| 台湾省| 绥德县| 莱芜市| 湟源县| 安化县| 遂宁市|