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BPS Bioscience Inc.
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當前位置:BPS Bioscience Inc.>>Coronavirus Assay Kits>> 78018Spike S1 RBD (SARS-CoV-2): ACE2 Inhibitor Screening Colorimetric Assay Kit

Spike S1 RBD (SARS-CoV-2): ACE2 Inhibitor Screening Colorimetric Assay Kit

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產品型號78018

品       牌BPS Bioscience

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更新時間:2023-11-12 16:28:50瀏覽次數:197次

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●Purchase●DescriptionThepandemiccoronavirusdisease2019()iscausedbySevereAcuteRespiratorySyndromeCoronavirus2(SARS-CoV-2)
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Description

The pandemic coronavirus disease 2019 () is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As a first step of the viral replication strategy, the virus attaches to the host cell surface before entering the cell. The Receptor Binding Domain (RBD) of Spike protein recognizes and attaches to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. Drugs targeting the interaction between the Spike protein of SARS-CoV-2 and ACE2 may offer some protection against the viral infection.


The Spike RBD S1 (SARS-CoV-2):ACE2 Inhibitor Screening Colorimetric Assay Kit is designed for screening and profiling inhibitors of this interaction. The key to this kit is the high sensitivity of detection of ACE2-Biotin protein by Streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, Spike RBD protein is attached to a 96-well transparent plate. Next, ACE2-Biotin is incubated with Spike RBD on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce color, which can then be measured using a UV/Vis spectrophotometer microplate reader.

This product has been cited 2 times.

Synonyms
SARS-CoV-2 inhibition kit, ACE2 inhibition kit, SARS Colorimetric kit, Spike RBD kit

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