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目錄:杭州斯達(dá)特生物科技有限公司>>抗體/抗原>>流式抗體>> S0B5403FITC Rat Anti-Mouse CD163 Antibody (S-R608)

FITC Rat Anti-Mouse CD163 Antibody (S-R608)
  • FITC Rat Anti-Mouse CD163 Antibody (S-R608)
參考價(jià) 863
具體成交價(jià)以合同協(xié)議為準(zhǔn)
參考價(jià) 863
具體成交價(jià)以合同協(xié)議為準(zhǔn)
  • 品牌 Starter/斯達(dá)特
  • 型號(hào) S0B5403
  • 廠商性質(zhì) 生產(chǎn)商
  • 所在地 杭州市
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更新時(shí)間:2025-07-13 07:51:59瀏覽次數(shù):41評(píng)價(jià)

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FITC Rat Anti-Mouse CD163 Antibody (S-R608)

CD163 is a 130 kDa type I transmembrane glycoprotein and a member of the scavenger receptor cysteine-rich (SRCR) superfamily. It is exclusively expressed on monocytes and macrophages and is involved in the clearance and endocytosis of hemoglobin-haptoglobin complexes, which helps protect tissues from oxidative damage caused by free hemoglobin. The protein consists of nine SRCR domains, a single transmembrane segment, and a short cytoplasmic tail. CD163 is upregulated in macrophages during the switch to alternative activated phenotypes in inflammation and is considered a marker for anti-inflammatory macrophages. Elevated levels of soluble CD163, which result from the shedding of the membrane-bound form, have been observed in various acute and chronic inflammatory disorders, making it a potential biomarker for inflammation. Additionally, CD163 is being explored as a therapeutic target for delivering drugs to macrophages in inflammatory conditions.

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