久久国产精品午夜一区_91精品國產高清久久久久久91_?级毛片免费全部播放_欧美色图在线视频一区二区三区_国产综合亚洲一区二区三区_中文字幕熟女网_国产精品男人爽免费视频_九九无码网战_亚洲日本三级电影在线观看_欧美日韩DVD手机在线不卡

CD326, also known as EpCAM （epithelial cell adhesion molecule） or TACSTD1 （tumor-associated calcium signal transducer 1）, is a 40 kDa type I transmembrane glycoprotein that serves as a calcium-independent homophilic cell adhesion molecule in the basolateral membranes of most epithelial cells. It plays a crucial role in cell adhesion, proliferation, and differentiation, and is highly expressed in various normal epithelial tissues, such as the gastrointestinal tract and liver. However, its expression is significantly upregulated in many epithelial cancers, including colorectal, breast, and prostate cancers, making it a valuable tumor marker. In cancer biology, CD326 is involved in tumor progression, metastasis, and the maintenance of cancer stem cells. It also has potential therapeutic applications, such as targeted drug delivery and immunotherapy, due to its specific expression on cancer cells.