久久国产精品午夜一区_91精品國產高清久久久久久91_?级毛片免费全部播放_欧美色图在线视频一区二区三区_国产综合亚洲一区二区三区_中文字幕熟女网_国产精品男人爽免费视频_九九无码网战_亚洲日本三级电影在线观看_欧美日韩DVD手机在线不卡

CD103, also known as integrin αEβ7, is a transmembrane heterodimeric receptor primarily expressed on the surface of certain immune cells, including intraepithelial lymphocytes （IELs）, tissue-resident memory T cells, and dendritic cells. It plays a crucial role in cell adhesion and migration by binding to E-cadherin, a protein abundant in epithelial cells, thereby facilitating immune cell retention within mucosal tissues such as the skin, lung, and gastrointestinal tract. In cancer immunology, CD103 is associated with immune checkpoint pathways and has been identified as a potential biomarker for predicting responses to immunotherapies, such as anti-PD-1 treatments. Additionally, CD103+ dendritic cells are known for their ability to cross-present antigens to CD8+ T cells, enhancing adaptive immune responses.