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BOB-1 interacts with the sequence-specific DNA-binding POU transcription factors （named after the founding family members PIT1, OCT1/2, and UNC86）, the ubiquitously expressed OCT1 （POU2F1） and lymphoid-specific OCT2 （POU2F2） [PMID: 33864944

IF: 9.2 Q1 B1]. As a transcriptional co-activator, BOB-1 itself does not bind DNA but is rather recruited into transcriptional regulation via interaction with DNA-bound POU-domain transcription factors OCT1 and OCT2. The POU-domain is a unique bipartite structure allowing DNA recognition with remarkable flexibility [PMID: 12213595

IF: 5.3 Q1 B2, PMID: 29335749

IF: 6.2 Q1 B2].