細胞壓力儀應用文獻

品牌美國flexcell ，型號：FX-5000C

美國Flexcell公司專注于細胞組織應力（牽張拉伸應力、三維水凝膠牽張拉伸應力、壓應力和流體切應力等）加載刺激培養(yǎng)產品的設計和制造，提供*的體外細胞拉應力、壓應力和流體剪切應力加載刺激與立體水凝膠支架三維細胞組織牽拉加載培養(yǎng)系統(tǒng)而*。其產品成熟度高、成功應用文獻量達4000多篇，國內有包括上海交通大學、復旦大學、同濟大學、上海第九醫(yī)院、中科院力學所、北京大學第三醫(yī)院、北航生物與醫(yī)學工程學院、都醫(yī)科大學、廣州醫(yī)科大學、南方科技大學、福建協(xié)和醫(yī)院、南方醫(yī)科大學近100家成功高校、醫(yī)院及基礎科研單位使用，無技術風險和使用風險，flexcell體外高通量細胞牽張拉伸力、壓應力以及流體剪切力加載培養(yǎng)系統(tǒng)已成為細胞力學體外加載模型的黃金標準，是細胞組織力學研究者的shou選。

 FX-5000C細胞壓力加載培養(yǎng)與實時觀察系統(tǒng)(flexcell FX5000 Compression system)現貨銷售，介紹如下：

FX-5000C對各種組織，三維細胞培養(yǎng)物提供壓力加載
計算機控制的壓力加載系統(tǒng)，對各種組織，三維細胞培養(yǎng)物提供周期性的或靜態(tài)的壓力加載
夾在活塞和固定臺之間的BioPress細胞培養(yǎng)板可承受正壓力的大值為14磅，小值為0.1磅。
檢測各種組織和細胞在壓力作用下的生物化學反應，例如：軟骨組織，椎間盤骨組織，肌腱組織，韌帶組織，以及從肌肉，肺，心臟，血管，皮膚，肌腱，韌帶，軟骨和骨中分離出來的細胞。
在主機的控制下，壓力傳導儀內的密封閥門裝置自動調節(jié)和控制壓力。
活塞和固定臺在BioPress細胞培養(yǎng)板或者StagePresser顯微儀器上擠壓樣品。
同一程序中可以同時運行多種頻率，多種振幅和多種波形
同時兼容四個獨立的FlexLink壓力加載和/或應力加載傳導儀。
更好地控制在超低或超高壓力下的波形。
頻率在0.01- 5 Hz。
多種波形種類：
靜態(tài)波形
正旋波形
心動波形
三角波形
矩形波形
各種特制波形

細胞壓力實驗裝置應用文獻：

[1] Baccam A, Benoni-Sviercovich A, Rocchi M, Moresi V, Seelaender M, Li Z, et al. The Mechanical Stimulation of Myotubes Counteracts the Effects of Tumor-Derived Factors Through the Modulation of the Activin/Follistatin Ratio. Frontiers in physiology. 2019;10:401.
[2] Bhattacharya MR, Bautista DM, Wu K, Haeberle H, Lumpkin EA, Julius D. Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons. Proceedings of the National Academy of Sciences of the United States of America. 2008;105:20015-20.
[3] Bianchi F, George JH, Malboubi M, Jerusalem A, Thompson MS, Ye H. Engineering a uniaxial substrate-stretching device for simultaneous electrophysiological measurements and imaging of strained peripheral neurons. Medical engineering & physics. 2019;67:1-10.
[4] Boyle ST, Kular J, Nobis M, Ruszkiewicz A, Timpson P, Samuel MS. Acute compressive stress activates RHO/ROCK-mediated cellular processes. Small GTPases. 2018:1-17.
[5] Dolzani P, Assirelli E, Pulsatelli L, Meliconi R, Mariani E, Neri S. Ex vivo physiological compression of human osteoarthritis cartilage modulates cellular and matrix components. PloS one. 2019;14:e0222947.
[6] Fang B, Liu Y, Zheng D, Shan S, Wang C, Gao Y, et al. The effects of mechanical stretch on the biological characteristics of human adipose-derived stem cells. Journal of cellular and molecular medicine. 2019;23:4244-55.
[7] Friedrich O, Merten AL, Schneidereit D, Guo Y, Schurmann S, Martinac B. Stretch in Focus: 2D Inplane Cell Stretch Systems for Studies of Cardiac Mechano-Signaling. Frontiers in bioengineering and biotechnology. 2019;7:55.
[8] He YB, Liu SY, Deng SY, Kuang LP, Xu SY, Li Z, et al. Mechanical Stretch Promotes the Osteogenic Differentiation of Bone Mesenchymal Stem Cells Induced by Erythropoietin. Stem cells international. 2019;2019:1839627.
[9] Hilscher MB, Sehrawat T, Arab JP, Zeng Z, Gao J, Liu M, et al. Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension. Gastroenterology. 2019;157:193-209 e9.
[10] Kanzaki H, Wada S, Yamaguchi Y, Katsumata Y, Itohiya K, Fukaya S, et al. Compression and tension variably alter Osteoprotegerin expression via miR-3198 in periodontal ligament cells. BMC molecular and cell biology. 2019;20:6.
[11] Klymenko Y, Wates RB, Weiss-Bilka H, Lombard R, Liu Y, Campbell L, et al. Modeling the effect of ascites-induced compression on ovarian cancer multicellular aggregates. Disease models & mechanisms. 2018;11.
[12] Liang X, Wang Z, Gao M, Wu S, Zhang J, Liu Q, et al. Cyclic stretch induced oxidative stress by mitochondrial and NADPH oxidase in retinal pigment epithelial cells. BMC ophthalmology. 2019;19:79.
[13] Liu Y, Huang X, Yu H, Yang J, Li Y, Yuan X, et al. HIF-1alpha-TWIST pathway restrains cyclic mechanical stretch-induced osteogenic differentiation of bone marrow mesenchymal stem cells. Connective tissue research. 2019;60:544-54.
[14] Matheson LA, Fairbank NJ, Maksym GN, Paul Santerre J, Labow RS. Characterization of the Flexcell Uniflex cyclic strain culture system with U937 macrophage-like cells. Biomaterials. 2006;27:226-33.
[15] Spassov SG, Kessler C, Jost R, Schumann S. Ventilation-Like Mechanical Strain Modulates the Inflammatory Response of BEAS2B Epithelial Cells. Oxidative medicine and cellular longevity. 2019;2019:2769761.
[16] van Kelle MAJ, Khalil N, Foolen J, Loerakker S, Bouten CVC. Increased Cell Traction-Induced Prestress in Dynamically Cultured Microtissues. Frontiers in bioengineering and biotechnology. 2019;7:41.
[17] Zhang J, Xu S, Zhang Y, Zou S, Li X. Effects of equibiaxial mechanical stretch on extracellular matrix-related gene expression in human calvarial osteoblasts. European journal of oral sciences. 2019;127:10-8.