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The DNASwift™ SAX-1S is a strong anion-exchange column that provides exceptionally high resolution for the purification of oligonucleotides. The exceptionally high resolution provides superior purity and yields compared to other ion-exchange or reversed-phase columns available. The DNASwift column is ideal for therapeutic and diagnostic research, which have very high purity and yield oligonucleotides purification requirements.
Highest resolution for oligonucleotide purification available, providing high purity and yields.
Exceptionally high capacity provides exceptionally high yields with high purity.
Refined selectivity, as with the DNAPac® column, for high resolution
Compatible with high pH, solvents, and high temperatures.
DNASwift SAX-1S Specifications Surface chemistry Quaternary amine Column dimension 5 × 150 mm Base matrix Polymethacrylate Oligonucleotide binding capacity ~20 mg/mL 20-mer Total binding capacity per column ~50 mg 20-mer Bed height 130 mm Bed volume 2.5 mL pH Range 6–12.4 for operation 2–14 for cleaning NOTE: [Salt]≥Equimolar to [NaOH] required Recommended Ffow rate 0.5–2.5 mL/min Maximum flow rate 3 mL/min Operating column pressure ≤ 1500 psi 10.3 MPa Maximum operating temperature 85 °C Solvent compatibility Most common organic solvents (e.g., CH3CN, CH3OH)